临床与实验眼科学杂志
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Changes in Ocular Surface Indices in Myopia Patients Undergoing Small Incision Lenticule Extraction (SMILE) Surgery

Yogesh Yadav, Vijay Kumar Sharma, Radhika Gupta, Prakhar Kumar Singh, Tanmay Mohapatra, Santosh Kumar

Aim: To study change in ocular surface indices in low and high myopia patient’s undergoing Small Incision Lenticule Extraction (SMILE) surgery.

Materials and methods: This was a prospective interventional study. We included 100 myopia patients (50 low myopia <5.0 D and 50 high myopia ≥ 5.0 D). Ocular Surface Disease Index Score (OSDI), Schirmer I Test (SIT) and Tear Breakup Time (TBUT) and other parameters were noted one week before and one week, four weeks, three months’ post-surgery.

Results: Mean values of SIT (mm/5 min) (low myopia is preoperative one week 29.6, postoperative one week 27.64, four weeks 28.75, three months 29.8 and in high myopia is preoperative one week 30.39, postoperative one week 28.67, four weeks 28.85, three months 30.77) showed significant fall in post-operative one week with continuous improvement thereafter, leading to comparable values with baseline in both subgroups. Similar trends were seen with mean values of OSDI (low myopia is preoperative one week 5.21, postoperative one week 12.14, four weeks 9.33, three months 4.72 and in high myopia is preoperative one week 4.07, postoperative one week 13.38, four weeks 9.36, three months 5.24) in both the groups. Mean values of TBUT (secs) (low myopia I preoperative one week 10.6, postoperative one week 8.83, four weeks 9.44, three months 10.17 and in high myopia is preoperative one week 11.2, postoperative one week 8.19, four weeks 9.17, three months 10.48) also showed significant fall in values postoperatively and then normalising in both groups.

Conclusion: As a treatment option, SMILE offers excellent refraction correction, along with complete recovery for dry eye symptoms in both high and low myopia patients.