妇产科学
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抽象的

1999-2008 年日本合子双胞胎率的年度趋势及其与母亲年龄的关系

今泉洋子和早川一夫

目的：我们的目的是确定单卵（MZ）和异卵（DZ）双胞胎率的最新趋势及其与母亲年龄（MA）的关系。

研究设计：使用 1999 年至 2008 年日本生命统计数据估算同卵双胞胎和异卵双胞胎率。

Results: The DZ twinning rate per 1000 deliveries increased from 5.10 in 1999 to 7.66 in 2005 and decreased thereafter (5.98 in 2008). The MZ twinning rate increased significantly with an increase in MA in 2002, 2003, 2006, and 2008. Both the DZ and overall twinning rates increased significantly with an increase in MA in each year. From 1960- 1967 to 1999-2008, the DZ twinning rates increased 280% for MA 30-34 years, 290% for MA 35-39, and 370% for MA 40 and over. On the contrary, the MZ twinning rates remained nearly constant with MA for both periods.

结论： 2005年之前DZ双胞胎率呈上升趋势，此后呈下降趋势。2005年的同卵双胞胎率（7.66）比1955年至1967年（2.26）高出339%，而同卵双胞胎率在引进生殖技术前后保持不变。