临床毒理学杂志
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Comprehensive Mycotoxin Analysis: Adding Alternaria Toxins and Ergot Alkaloids to Multi-Mycotoxin Analysis in Various Food Commodities

Shun-Hsin Liang*

The ubiquitous contamination of food products with Alternaria Toxins (ATs) and Ergot Alkaloids (EAs) often goes unnoticed due to the lack of clear assessments of their human toxicity. To address this issue, a fast and Liquid Chromatography-Mass Spectrometry (LC-MS) friendly method was developed for the accurate and robust analysis of a total of 37 mycotoxins, including ATs and EAs, in various food commodities. This analytical workflow was established through a thorough examination of different types of LC bonding chemistries, sample extraction conditions, and calibration methodologies to ensure accuracy and precision in the measurement.