血液病与血栓栓塞疾病杂志
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Discrimination between Toxoplasmic Encephalitis and Central Nervous System Lymphoma: An Updated Review

Shingen Nakamura1*, Hirokazu Miki2

Various opportunistic infections, such as human immunodeficiency virus infections, develop in compromised hosts. The treatment options for Malignant Lymphoma (ML) and Toxoplasmic Encephalitis (TE) are completely different; therefore, discriminating between them is critical. Currently, imaging techniques such as magnetic resonance imaging, ²⁰¹Tl-single photon emission computed tomography, and 18F-fluorodeoxyglucose-positron emission tomography/computed tomography and laboratory techniques such as PCR and antibody assays are used. Moreover, there are options for pathological examination using brain biopsy. However, discriminating between ML and TE remains challenging. Here, we describe an update of the discrimination methods between TE and ML.