肝病与胃肠道疾病杂志
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氟桂利嗪控制酸中毒引起的头痛的有效性

萨加里卡·达塔

In my previous case report, I mentioned about the connection between metabolic acidosis and other diseases.
Headache is one of the diseases mentioned in a female patient. For the patient, it was observed that acidosis is the
indicator. Acidosis takes place first.
There can be many reasons for metabolic acidosis.
For this patient it was seen that, food is the trigger, with consistent misbalance in pH level in body it exhibits many
Symptoms like
Palpitations.
Optical swelling.
Shortness of breath.
Altered mental status such as severe anxiety due to hypoxia.
Nausea.
Abdominal pain.
Altered appetite and weight gain.
Muscle weakness, bone pain, and joint pain.
In acidosis the arterial carbon dioxide tension increases, and it can cross the blood-brain barrier and changes
extravascular pH, Headache is trigger.
Patient was treated with Pregabalin, Amitriptyline and Duloxetine combination.
Frequency of headache was less but it was not stopped. Then patient was treated with CGRP receptor blocker
subcutaneous injection but was not able to get rid of the throbbing head pain.
All the above medicines did not fully work because the type of headache may not be migraine.
On using Flunarizine (Sibelium 10 mg) the headache was stopped on second day of medicine taking. It helped in
reducing allergy-like symptoms too.
氟桂利嗪的钙通道阻断特性可能对偏头痛起作用，但氟桂利嗪的另一个特性，
控制中枢神经系统的二氧化碳张力，对酸中毒引起的头痛也有很大作用。因此，氟桂利嗪的以下特性
有助于控制头痛、
钙通道阻断，从而控制神经递质的释放。
控制中枢神经系统中的二氧化碳张力。
控制组胺发挥作用。
控制肥大细胞脱粒。
氟桂利嗪控制酸中毒相关头痛的有效性已得到充分证明。