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Extremities Muscles Weakness in Patients with Guillain-Barre Syndrome

Samia O. Massaad, Mohammed Ahmed A. Ahmed, Nassreen Khalid Hassan

Muscular weakness is one of the most common neurologic presentations in patients with Guillain-Barre Syndrome (GBS).

Objectives: The purpose of this study was to determine the muscles weakness distribution in the limbs in patients with Guillain-Barre syndrome.

Methods: This study was a descriptive cross-sectional study conducted in faculty of medicine, Gadarif university to determine the muscle weakness in extremities in patients with Guillain-Barre Syndrome in Gadarif, eastern Sudan. The data was collected from Gadarif pediatrics teaching hospital in Eastern Sudan during the period from January 2017 to December 2022.

Results: Forty-five (45) patients with diagnosed Guillain-Barre Syndrome were collected in the study period. There were 26 (57.8%) males and 19 (42.2%) females with a male to female ratio 1.4: 1. The mean age was 7.22 years ± 3.7 years (the age’s ≤ 15 years). 31 (68.8%) patients had symmetrical weakness in upper and lower limbs, of them, 19 (61.3%) patients had symmetrical lower limb weakness. Asymmetrical right lower and upper limb weakness was 4/6 and 5/8 respectively.

Conclusion: Symmetrical weakness was most prominent; in lower extremity weakness was most common proximally, while the distal weakness in UL was common in patients with Guillain-Barre syndrome.