麻醉与临床研究
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Incidence, Risks, Prevention and Management of Rebound Pain after Resolution of Peripheral Nerve Block. Systematic Review

Belete Muluadam Admassie*

Background: Rebound pain is severe pain experienced after the resolution of regional anesthesia. Both patients, surgical and anesthesia related factors affect incidence as well as the severity of rebound pain. Use of perioperative multimodal decreases incidence as well as the severity of rebound pain after resolution of peripheral nerve block. Therefore, this systematic review aimed to review about incidence, risk, prevention, and management of rebound pain after resolution of peripheral nerve block.

Methods: A medical search engines of PubMed, Google Scholar, Cochrane Review, and PubMed Centeral to get access for current and updated evidences on procedures on risk stratification, prevention and management of corneal abrasion for non-ocular surgery and we formulate the key questions, scope, and eligibility criteria for the articles to be included, advanced search strategy of electronic sources from databases and websites was conducted. Screening of literatures was conducted with proper appraisal checklist. This review was reported in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 statement.

Results: A total of 8767 articles were identified from databases and websites using an electronic search. Two hundred articles were removed for duplication and 7720 studies were excluded after reviewing titles and abstracts. At the screening stage, 1205 articles were retrieved and evaluated for eligibility. Finally, 50 studies met the eligibility criteria and were included in this systematic review.

Conclusions and recommendation: The overall incidence of rebound pain after PNB resolved may reach 61.7%. Both patients, surgical and anesthesia related factors affect incidence as well as the severity of rebound pain. Use of perioperative multimodal strategy decreases incidence as well as the severity of rebound pain after resolution of peripheral nerve block.