N'negue ep。Mezui-Mbeng M-A1*、Makoyo Komba O2、Bang Ntamack J A2、Nkolo Ovouele J-C1、Lendoye E1、Edou Engonga P3
Introduction: Aging is a slow and progressive process different from disease, whose main cause is the presence of free radicals and oxidative attacks on mitochondrial DNA in the body. The frequency of mitochondrial DNA deletions would increase exponentially from the age of 50 years to reach considerable levels in older people Objectives: To measure the antioxidant activity of the plasma of healthy women without chronic pathology whose etiology would be related to the oxidative stress, and whose age is lower or equal to 50 years, by scavenging of the free radical ABTS•+.The aim of the study is to observe the evolution of the antiradical capacity of the blood with age, up to 50 years.
Results: The mean antiradical activity of women of ages>40 years was 2.2% higher than that of women of age’s ≤ 40 years. The antiradical activity of overweight women with a Body Mass Index (BMI) greater than 25 and a mean age of 42.16 ± 7.78 years was more or less equivalent to that of normal-bodied women with a BMI less than 25 having a mean age of 36.25 ± 8.95 years. The mean antiradical activity of women with less than 3 gestation and a mean age of 32.25 ± 7.13% is little different from that of women with gestation of 3 or more with a mean age of 44.83 ± 4.35%. The mean antiradical activity of women with parities less than 3 and a mean age of 35 ± 7.32 years is equivalent to that of women with parities greater than or equal to 3 with a mean age of 47.83 ± 2.16%. The antiradical activity of the plasma of women consuming 2 to 3 fruits and vegetables per day with a mean age of 43.6 ± 4.39 is about 3.5% higher than those of women consuming only 1 fruit and vegetable/day with a mean age of 36 ± 10.07.
结论：通过自由基清除对女性血液总抗氧化能力进行的评估表明，50 岁以下女性的血浆中已经逐渐建立了轻微的氧化应激。水果和蔬菜的食用可以丰富机体的抗氧化化合物。 。gestité 和胎次大于或等于 3 可以减缓氧化应激的出现。