血液病与血栓栓塞疾病杂志
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Thromboembolism-Related Maternal Mortality: Incidence and Prophylactic Approaches

Mayke Koek*, Karlijn Scheepens, Esther Scheers

Thromboembolism is a leading cause of maternal mortality globally, but many cases are preventable. This study investigates the incidence and prophylactic strategies for maternal mortality due to thromboembolism during the postnatal period. The research employs ethical standards and security measures to collect and analyze data from mortality cases, comparing them with a healthy control group. Clinical manifestations, heparin administration, and risk factors are assessed using a structured questionnaire. The study reveals a maternal mortality rate of 16 per 100,000 live births, with 9% attributed to thromboembolism. Dyspnea is a common symptom, and heparin administration varies. Most cases occur within the first day post-delivery, highlighting the postpartum risk. The average risk score is 4.6, signifying a high risk population, but heparin administration remains inadequate. Cesarean sections and maternal BMI are factors of interest, and blood group A+ is prevalent among mothers. This study emphasizes the need for improved screening, standardized protocols, and comprehensive care for high risk pregnant and postpartum women to reduce maternal mortality due to thromboembolism.