临床与实验心脏病学
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Why is the Left Ventricular Global Longitudinal Strain Reduced in Idiopathic Inflammatory Myopathies?

Luiz S. G. Machado1, Ana C. D. Oliveira1, Frederico J. N. Mancuso2, Emilia Inoue Sato1*

In the study carried out by our group-first study demonstrating speckle tracking echocardiography has prognostic value in patients with idiopathic inflammatory myopathies. We demonstrated that patients with Idiopathic Inflammatory Myopathy (IIM) have lower mean Global Longitudinal Strain (GLS) of the Left Ventricle (LV) than controls, colloborating the results of two previous studies. In addition, we found that reduced LV GLS has prognostic value in the evolution of the disease. However, the reason to explain why patients with IIM have reduced LV GLS are still uncertain. We designed this small study to assess whether disease activity or duration could, in part, explain it.