蛋白质组学与生物信息学杂志
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Evaluation of Secondary and Tertiary Protein Structure Variation in rbcl Gene of Selected Legumes using Computational Approach

U. L. Edem

This research was conducted to assess variation in secondary and tertiary protein structure of rbcL gene of African Yam Bean (Sphenostylis sternocarpa), Phaseolus vulgaris, Vigna unguiculata, Vigna angularis, Glycine max and Cajanus cajan. The rbcL genes of the legume was downloaded from National Center for Biotechnology Information (NCBI) and subjected to multiple sequence alignment on Molecular Evolutionary Genetics Analysis (MEGA). Secondary and tertiary protein structure variations were determined using Goriv and Phyre 2 online computational analysis tools respectively. The phylogenetic relationship among the legumes divided them into two groups. Secondary protein structure subunits were similar among the legumes. However, the folding of the tertiary protein structure was different among the plants suggesting evolutionary actions on the rbcL gene overtime.