临床与实验眼科学杂志
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Examination of Risk Factors Influencing the Time to in-the-bag-Intraocular Lens Dislocation

Yoshiro Tokunaga, Eiichi Nishimura, Mitsutaka Soda

Purpose: To verify the risk factors that influences the Intraocular Lens (IOL) dislocation.

Materials and methods: The time to of in-the-bag IOL (242 eyes) dislocation after the initial surgery was examined using patient characteristics and risk factors. The examined risk factors included 11 factors associated with underlying diseases (trauma, Pseudoexfoliation Syndrome (PE), atopic dermatitis, retinitis pigmentosa, glaucoma attack, glaucoma, short axial length, long axial length, uveitis, scleral buckling, post-pars plana vitrectomy) and two factors associated with the initial surgical findings (Zonular Weakness (ZW), posterior capsule rupture). In addition, the 242 eyes were classified into four groups (group A, PE+ ZW+; group B, PE- ZW+; group C, PE+ ZW-; group D, PE- ZW-) and the dislocation period was examined.

Results: The median patient age was 67 years and the median time to dislocation after the first cataract surgery was 120 months. Among the risk factors, PE and ZW were significantly associated with the time to dislocation (both p<0.05). In addition, the time to dislocation was significantly shorter in groups A (12.3 months) and B (83.6 months) than in group D (135.6 months; p<0.001 and p=0.007, respectively).

Conclusion: The presence of PE and/or ZW increases the risk of IOL dislocation. However, positivity for PE alone may be associated with a lower risk of IOL dislocation, indicating the need to assess ZW in the initial surgery.