真菌基因组学与生物学
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Facial Sporotrichosis and Chromoblastomycosis in Madagascar: Serial Cases

M Andrianarison*, MF Rakotosaona, F Rapelanoro Rabenja, FA Sendrasoa, TM Rasamoelina, M Sata, LS Ramarozatovo, IM Ranaivo

Objective: Our study aims to determine the epidemiological and clinical management of deep facial mycosis cases.

Methods: We have conducted a prospective descriptive study of facial sporotrichosis and chromoblastomycosis cases at the two dermatology departments of Antananarivo university hospital to document current various forms of facial infections.

Results: During a period of five years, from 2013 to 2017, 148 cases of subcutaneous implantation fungal infection were founded, including 63 cases (42.6%) of sporotrichosis and 50 cases (33.9%) of chromoblastomycosis. Nine cases (6%) on the face have been recorded, 5 of which are children aged 5 to 15. Infections are mostly located on the palpebral region, affecting 80% of the screened patients. All patients were treated orally with itraconazole.

Conclusion: Subcutaneous mycoses mainly affect children, either by self-inoculation or by co-infection of other members of the family. The lesions are serious with severe aesthetic damage. Itraconazole is an effective treatment in both adults and children.