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Prune-Belly Syndrome Fertility: Is Fertility Fruitful or Futile

Lane Shish*, Stanley Kogan

Patients with Prune-Belly Syndrome (PBS) have historically been considered infertile, however significant improvements in medical care, research and reproductive technologies have greatly improved their reproductive capabilities. Our recent scoping review reviewing the extant literature over the last 70 years demonstrated favorable testicle histology, sex hormone profiles, semen analyses and successful conception potential in PBS patients. Despite their fertility potential, specialized and individualized guidance is needed to help manage their reproductive needs.