临床儿科学：开放获取
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Infantile Pyknocytosis: The Presence of Abnormal Erythrocytes in Newborn and Infants

Hesam Saeidian

Infantile pyknocytosis is a rare blood disorder that primarily affects newborns and infants. Characterized by the presence of abnormal red blood cells called pyknocytes, this condition can cause mild to severe symptoms, including anemia and jaundice. While infantile pyknocytosis is typically benign and self-limiting, understanding its causes, symptoms and management is crucial for proper diagnosis and care. Diagnosis is exclusively based on the detection of a higher proportion of pyknocytes in peripheral blood smear. IP is a self-restricted disease. In this case series study we present the diagnostic approach. IP should be included in the differential diagnosis in case of prolonged neonatal jaundice not well explained by other common of hemolytic anemia.